How ONKONEK Works
THE NATURE OF THE BEAST
Cancer is like an out of control car
The accelerator is jammed on and the brakes don’t work
Effects on the normal cell of genetic cancer causing mutations
NORMAL CELLS WITH ONCOGENIC GENETIC MISTAKES SELF-DESTRUCT (APOPTOSIS)
Apoptosis is committing suicide which is an act requiring energy
CANCER CELLS AVOID APOPTOSIS
They do this by restricting their available energy so there is
not enough for them to kill themselves
Cancer cells are addicted to division.
Without sufficient energy normal cells stop dividing.
Onkonek lowers the energy just enough so cancer cells die as they divide.
Turning Down the Energy of Cancer Cells
Cancer cells have to closely control the energy molecule ATP inside them. Too much energy and they commit suicide (Apoptosis). Too little energy and they are not able to survive (Necrosis).
ONKONEK turns down the energy controlling “Thermostat” much lower than the cancer cell needs or can tolerate. There is not enough energy to maintain important normal functions including the pumps that maintain the gradient across the cell membrane so that the cell effectively “drowns”.
NECROSIS
Low Energy
APOPTOSIS
High Energy
SYNTHERIX’s lead agent ONKONEK works in a novel way which should avoid the side-effects of chemotherapy and immunotherapy because it does not affect normal cells.
ONKONEK also has a broad global effect against most different types of cancer.